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By generating starvation- resistant flies through experimental evolution, these researchers at UNLV were able to more closely observe the relationships between sleep behavior, feeding, foraging, and starvation resistance. Because sleep and feeding are related to metabolic rates, they could potentially contribute to Drosophila melanogaster resistance under starvation conditions. The flies used in this experiment have been bred over 60 generations in order to become starvation resistant. These flies were bred on an agar diet that was devoid of calories, and live around 18 days when under starvation conditions. Flies that have not been selected for starvation resistance survive around 2-3 days.
Ethanol Sensitivity and Tolerance in Long-Term Memory Mutants of Drosophila melanogaster - Berger - 2008 - Alcoholism: Clinical and Experimental Research - Wiley Online Library Mutants of the learning and/or memory pathways have differential responses to ethanol tolerance. Some mutants increased amnesia/learning loss, while others had an opposite effect to ethanol tolerance. Researchers tested a collection of 60 long-term memory mutants for 52 loci where these mutants limit learning so normal function of each mutation are thought to play into the long-term memory pathway. Researchers then ran an ethanol assay and quantified the ethanol tolerance of each mutant. The data suggests that these pathways overlap and suggest specific genes for each pathway.